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J Pachón Selected Research

Imipenem

1/2016Efficacy of Lysophosphatidylcholine in Combination with Antimicrobial Agents against Acinetobacter baumannii in Experimental Murine Peritoneal Sepsis and Pneumonia Models.
5/2013Inoculum effect on the efficacies of amoxicillin-clavulanate, piperacillin-tazobactam, and imipenem against extended-spectrum β-lactamase (ESBL)-producing and non-ESBL-producing Escherichia coli in an experimental murine sepsis model.
7/2011Efficacy of rifampin, in monotherapy and in combinations, in an experimental murine pneumonia model caused by panresistant Acinetobacter baumannii strains.
2/2011Local imipenem activity against Pseudomonas aeruginosa decreases in vivo in the presence of siliconized latex.
4/2005Pharmacokinetic/pharmacodynamic assessment of the in-vivo efficacy of imipenem alone or in combination with amikacin for the treatment of experimental multiresistant Acinetobacter baumannii pneumonia.
1/2005Activity of cefepime and carbapenems in experimental pneumonia caused by porin-deficient Klebsiella pneumoniae producing FOX-5 beta-lactamase.
10/2004Morphological changes induced by imipenem and meropenem at sub-inhibitory concentrations in Acinetobacter baumannii.
6/2004Colistin efficacy in an experimental model of Acinetobacter baumannii endocarditis.
4/2001Sulbactam efficacy in experimental models caused by susceptible and intermediate Acinetobacter baumannii strains.
2/2001Case-control study of risk factors for the development of enterococcal bacteremia.
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J Pachón Research Topics

Disease

13Pneumonia (Pneumonitis)
01/2016 - 04/2000
11Infections
11/2021 - 01/2000
7Sepsis (Septicemia)
11/2021 - 03/2008
4Bacteremia
01/2016 - 02/2001
3Coinfection
11/2012 - 05/2011
3Human Influenza (Influenza)
11/2012 - 01/2012
3Meningitis
03/2008 - 12/2000
3Endocarditis
06/2004 - 02/2001
3Acquired Immunodeficiency Syndrome (AIDS)
06/2001 - 04/2001
2Bacterial Infections (Bacterial Infection)
01/2016 - 01/2000
2Foreign Bodies (Foreign Body)
02/2012 - 02/2011
1Body Weight (Weight, Body)
01/2016
1Intraabdominal Infections
05/2013
1Hematologic Neoplasms (Hematological Malignancy)
04/2012
1Diabetes Mellitus
01/2012
1Morbid Obesity
05/2011
1Peritonitis
02/2011
1Cross Infection (Nosocomial Infection)
07/2010
1Superinfection
07/2010
1Febrile Neutropenia
01/2010
1Healthcare-Associated Pneumonia
10/2004
1Osteomyelitis
06/2004
1Retinitis
06/2001
1Cytomegalovirus Retinitis
06/2001
1Progressive Multifocal Leukoencephalopathy
04/2001
1Cholangitis
04/2001
1Infertility (Sterility)
04/2001
1Fibrosis (Cirrhosis)
02/2001
1Neutropenia
02/2001
1Fever (Fevers)
12/2000
1Echinococcosis (Hydatid Cysts)
07/2000
1Leukocytosis (Pleocytosis)
01/2000
1Bacterial Meningitis
01/2000

Drug/Important Bio-Agent (IBA)

11ImipenemFDA Link
01/2016 - 04/2000
4Colistin (Coly-Mycin)FDA Link
01/2016 - 12/2000
3Carbapenems (Carbapenem Antibiotics)IBA
11/2021 - 01/2005
3Anti-Bacterial Agents (Antibiotics)IBA
11/2014 - 11/2003
3Antiviral Agents (Antivirals)IBA
11/2012 - 01/2012
2Tigecycline (Tygacil)FDA Link
01/2016 - 07/2010
2Levofloxacin (Levaquin)FDA Link
07/2013 - 07/2008
2FluoroquinolonesIBA
07/2013 - 07/2008
2Ciprofloxacin (Cipro)FDA LinkGeneric
07/2013 - 07/2008
2Amoxicillin (Wymox)FDA LinkGeneric
05/2013 - 06/2008
2Clavulanic Acid (Potassium Clavulanate)FDA LinkGeneric
05/2013 - 06/2008
2SulbactamFDA LinkGeneric
07/2011 - 04/2001
2PorinsIBA
07/2008 - 01/2005
2Amikacin (A.M.K)FDA LinkGeneric
04/2005 - 04/2000
2Meropenem (Merrem)FDA LinkGeneric
01/2005 - 10/2004
2SodiumIBA
03/2002 - 12/2000
1carbapenemaseIBA
11/2021
1Anti-Infective Agents (Microbicides)IBA
01/2016
1Interleukin-10 (Interleukin 10)IBA
01/2016
1Lysophosphatidylcholines (Lysophosphatidylcholine)IBA
01/2016
1Tazobactam Drug Combination Piperacillin (Zosyn)FDA LinkGeneric
05/2013
1CoagulaseIBA
02/2013
1Methicillin (Metin)FDA Link
08/2012
1Adrenal Cortex Hormones (Corticosteroids)IBA
04/2012
1DaptomycinFDA Link
02/2012
1VancomycinFDA LinkGeneric
02/2012
1cecropin AIBA
11/2011
1Peptides (Polypeptides)IBA
11/2011
1Melitten (Melittin)IBA
11/2011
1UB 8902IBA
10/2011
1Rifampin (Rifampicin)FDA LinkGeneric
07/2011
1Oseltamivir (Tamiflu)FDA Link
05/2011
1SiliconesIBA
02/2011
1QuinolonesIBA
07/2008
1Cefotaxime (Kendrick)FDA LinkGeneric
06/2008
1Cefoxitin (Cefoxitin Sodium)FDA LinkGeneric
06/2008
1beta-lactamase FOX-5IBA
01/2005
1Cefepime (Maxipime)FDA LinkGeneric
01/2005
1Cyclosporine (Ciclosporin)FDA LinkGeneric
03/2002
1Azathioprine (Imuran)FDA LinkGeneric
03/2002
1Prednisone (Sone)FDA LinkGeneric
03/2002
1Antilymphocyte Serum (Anti-Thymocyte Globulin)IBA
03/2002
1Mycophenolic Acid (Cellcept)FDA LinkGeneric
03/2002
1Ganciclovir (Cytovene)FDA LinkGeneric
06/2001
1A-factor (Streptomyces)IBA
06/2001
1Cidofovir (Vistide)FDA Link
04/2001
1Cephalosporins (Cephalosporin Antibiotics)IBA
02/2001
1Praziquantel (Biltricide)FDA Link
07/2000
1Albendazole (Albenza)FDA Link
07/2000
1Doxycycline (Periostat)FDA LinkGeneric
04/2000
1Interleukin-8 (Interleukin 8)IBA
01/2000
1InterleukinsIBA
01/2000
1Biomarkers (Surrogate Marker)IBA
01/2000
1Interleukin-1beta (Interleukin 1 beta)IBA
01/2000
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2000
1Interleukin-6 (Interleukin 6)IBA
01/2000

Therapy/Procedure

9Therapeutics
11/2014 - 06/2001
5Length of Stay
02/2013 - 12/2000
2Artificial Respiration (Mechanical Ventilation)
11/2014 - 11/2012
2Transplantation
01/2012 - 03/2002
2Catheters
03/2008 - 02/2001
2Prostheses and Implants (Prosthesis)
11/2003 - 04/2001
1Highly Active Antiretroviral Therapy (HAART)
04/2001
1Parenteral Nutrition
02/2001
1Urinary Catheters
02/2001
1Organ Transplantation
02/2001
1Neurosurgical Procedures
01/2000